Page 111 - A Magyar Szemorvostársaság 2023. évi kongresszusa - Tudományos program és előadáskivonatok

specificitás 67% (95%CI: 51–79%) és 99% (95%CI: 85–100%) volt, és 71% (95%CI: 60–80%)
és 63% (95%CI: 49–51%), amennyiben a kontrollok nem-neovaszkuláris AMD-s betegek
voltak. Összességében az egyes tanulmányokban az elfogultság potenciális forrásai
alacsonyak voltak.

Következtetés és Jelentőség: Annak ellenére, hogy az Amsler-rács a metamorphopsia
detektálásnak egy egyszerű és olcsó módja, a szenzitivitása olyan szinten lehet, amely mellett
jellemzően nem ajánlott a monitorizálás. Ezt összekötve a neovaszkuláris AMD
rizikócsoportokban történő azonosításra vonatkozó mindössze közepes specificitásával, ez
utóbbi betegek számára valószínűleg javasolt a rendszeres szemészeti vizsgálat, az Amsler-
rács eredményétől függetlenül is.

Diagnostic Accuracy of the Amsler Grid Test for Detecting Neovascular Age-Related
Macular Degeneration: A Meta-Analysis
3,4
2,1
1
Bjerager Jakob , Schneider Miklós , Potapenko Ivan , van Dijk Elon H. C. , Faber
1
11
Carsten , Grauslund Jakob 6,7,8 , Pfau Kristina 9,10 , Huemer Josef , Muttuvelu Danson
1,5
V. 1,12 , Rasmussen Marie L. R. , Sabaner M. Cem , Subhi Yousif
1,7
1,5
13
1 Department of Ophthalmology, Rigshospitalet Glostrup, Glostrup, Denmark
2 Department of Ophthalmology, Semmelweis University, Budapest, Hungary
3 Department of Ophthalmology, Leiden University Medical Centre, Leiden, The Netherlands
4 Department of Ophthalmology, Haga Hospital, The Hague, The Netherlands
5 Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
6 Department of Ophthalmology, Odense University Hospital, Odense, Denmark
7 Department of Clinical Research, University of Southern Denmark, Odense, Denmark
8 Department of Ophthalmology, Vestfold Hospital Trust, Tønsberg, Norway
9 Department of Ophthalmology, University Hospital Bonn, Bonn, Germany
10 Department of Ophthalmology, University Hospital Basel, Basel, Switzerland
11 NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS
Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom
12 MitØje Aps, Skive, Denmark
13 Department of Ophthalmology, Kütahya Health Sciences University, Evliya Celebi Training
and Research Hospital, Kütahya, Turkey

Importance: Patients with non-neovascular age-related macular degeneration (AMD) are
encouraged to use the Amsler grid for self-assessment to facilitate early diagnosis. The test is
widely recommended, suggesting that it signals worsening warranting its use in home
monitoring of AMD.

Objective: To systematically review studies of the diagnostic test accuracy of the Amsler grid
in the diagnosis of neovascular AMD and to perform diagnostic test accuracy meta-analyses.

Data Sources: A systematic literature search was conducted in 12 literature databases for
relevant titles from database inception until May 7th, 2022.

Study Selection: Studies with groups defined as having 1) neovascular AMD and 2) either
healthy eyes or eyes with non-neovascular AMD. The index test was the Amsler grid. The
reference standard was ophthalmic examination. After removal of obviously irrelevant reports,
two authors independently screened remaining references in full text for potential eligibility.
Disagreements were resolved by a third author.