Page 55 - Magyar Gasztroenterológiai Társaság 2020. november 6–7. – ONLINE KONGRESSZUS

Előadáskivonatok / Abstracts

is open for all national centers, which can provide valuable

Introduction: Small-bowel tumours account for 1 % - 3 % of is open for all national centers, which can provide val
data. We plan to extend data collection internationally. uable
Introduction: Small-bowel tumours account for 1 % - 3 % of
all gastrointestinal neoplasms. Video capsule endoscopy Results: Data collection will help to determine factors
data. We plan to extend data collection internationally.
Results: Data collection will help to determine factors
(VCE) suggests that the frequency of these tumours may be associated with risk of NASH development and to get closer
all gastrointestinal neoplasms. Video capsule endoscopy
substantially higher than previously reported. The small to the pathomechanisms responsible for the liver fibrosis
(VCE) suggests that the frequency of these tumours may be
associated with risk of NASH development and to get closer
substantially higher than previously reported. The small
bowel represents 90 % of the overall mucosal surface of the to the pathomechanisms responsible for the liver fibrosis
progression.
bowel represents 90 % of the overall mucosal surface of the
alimentary tract, it is considered a rare location for the progression.
Conclusions: The objective of this registry is to document
development of neoplasms. Small-bowel tumours grow the clinical course of NAFLD/NASH disease, to evaluate the
Conclusions: The objective of this registry is to document
alimentary tract, it is considered a rare location for the
the clinical course of NAFLD/NASH disease, to evaluate the
development of neoplasms. Small-bowel tumours grow
slowly, extraluminally, remaining asymptomatic for years or effectivity of treatment and to develop a database for clinical
studies and establish a network for research cooperation in
slowly, extraluminally, remaining asymptomatic for years or
presenting insidiously in patients with nonspecific complaints effectivity of treatment and to develop a database for clinical
presenting insidiously in patients with nonspecific complaints
Central and Eastern Europe. ork for research cooperation in
such as abdominal pain, diarrhoea, iron deficiency anaemia, studies and establish a netw
bleeding, extraintestinal symptoms iron deficiency anaemia, Central and Eastern Europe.
such as abdominal pain, diarrhoea,
Case description: Gy.L. 56 years old male. Medical history: 55. PRE-TRANSPLANT SARCOPENIC OBESITY

bleeding, extraintestinal symptoms
LIVER
Case description: Gy.L. 56 years old male. Medical history:
PRE-TRANSPLANT
LC, T2DM, BPPV, Cataract NAFLD, kidney stones. ACBG WORSENS THE SURVIVAL AFTER OBESITY
55.
SARCOPENIC
A
PROTOCOL
A
WORSENS
surgery, anticoagulant therapy was initiated. He was TRANSPLANTATION: SURVIVAL AFTER OF LIVER
LC, T2DM, BPPV, Cataract NAFLD, kidney stones. ACBG
THE
TRANSPLANTATION:
PROTOCOL
OF
A
investigated for anaemia and positive FOBT from 2017. Only PROSPECTIVE AND A RETROSPECTIVE COHORT A
surgery, anticoagulant therapy was initiated. He was
STUDY
investigated for anaemia and positive FOBT from 2017. Only
diminutive polyps found by repeated gastroscopy and PROSPECTIVE AND A RETROSPECTIVE COHORT
STUDY
colonoscopy In 2018. he was admitted to our outpatient video Hegyi P. , Váncsa S. , Hegyi P. 1,2,3 , Pár G.
diminutive polyps found by repeated gastroscopy and
1
3
1,3
capsule endoscopic (VCE) centre. The capsule (Given 1. Institute for Translational Medicine, Medical School,
1,3
, Pár G.
3
1
1,2,3
colonoscopy In 2018. he was admitted to our outpatient video
Hegyi P. , Váncsa S. , Hegyi P.
capsule endoscopic (VCE) centre. The capsule (Given
1. Institute for Translational Medicine, Medical School,
Imaging) cruised with normal peristaltic term into the small- University of Pécs, Pécs, Hungary; 2. First Department of
bowel and showed two polyps in the jejuno ileal border and Medicine, University of Szeged, Szeged, Hungary; 3.
University of Pécs, Pécs, Hungary; 2. First Department of
Imaging) cruised with normal peristaltic term into the small-
Medicine, University of Szeged, Szeged, Hungary; 3.
in the proximal part of the ileum. Both of the diameters were Division of Gastroenterology, First Department of Medicine,
bowel and showed two polyps in the jejuno ileal border and
in the proximal part of the ileum. Both of the diameters were
Division of Gastroenterology, First Department of Medicine,
8-10 mm. The covering mucosa was damaged and showed. Medical School, University of Pécs, Pécs, Hungary
8-10 mm. The covering mucosa was damaged and showed.
oozing of blood. Surgical resection was done. Histology Medical School, University of Pécs, Pécs, Hungary

gastric
metaplasia.
with
No
hamartomas
oozing
verified of blood. Surgical resection was done. Histology Introduction: Non-alcoholic fatty liver disease became the
hamartomas
complications were found, the patient recovered. The was no second leading aetiology of liver disease among adults
Introduction: Non-alcoholic fatty liver disease became the
metaplasia.
No
verified
gastric
with
second leading aetiology of liver disease among adults
recurrence of anaemia or positive FOBT during follow up. awaiting liver transplantation (LT) and it is predicted to
complications were found, the patient recovered. The was no
Conclusion: VCE is an accurate, safe, and painless method become the leading indication for LT by 2030. These patients
recurrence of anaemia or positive FOBT during follow up.
awaiting liver transplantation (LT) and it is predicted to
of endoscopically evaluating all of the small bowels. The VCE often develop obesity and sarcopenia simultaneously, coined
Conclusion: VCE is an accurate, safe, and painless method
become the leading indication for LT by 2030. These patients
is the authentical method of evaluating the origin of occult often develop obesity and sarcopenia simultaneously, coined
as sarcopenic obesity (SO).
of endoscopically evaluating all of the small bowels. The VCE
is the authentical method of evaluating the origin of occult
gastrointestinal bleeding even caused rare small intestinal Aim: Our study aims to investigate whether the incorporation
as sarcopenic obesity (SO).
tumours. Aim: Our study aims to investigate whether the incorporation
of pre-transplant body composition into prognostic scores
gastrointestinal bleeding even caused rare small intestinal
tumours. of pre-transplant body composition into prognostic scores
results in a formula with high predictive accuracy for post-
54. NON-ALCOHOLIC FATTY LIVER DISEASE/ NON- transplant outcomes. with high predictive accuracy for post-
results in a formula

ALCOHOLIC STEATOHEPATITIS DISEASE REGISTRY IN Methods: The cohort study consists of retrospective and
54. NON-ALCOHOLIC FATTY LIVER DISEASE/ NON-
transplant outcomes.
prospective parts, planned and carried out by the Hungarian
ALCOHOLIC STEATOHEPATITIS DISEASE REGISTRY IN
HUNGARY: A PROTOCOL Methods: The cohort study consists of retrospective and
1
1,2
3
HUNGARY: A PROTOCOL
4
Hegyi P. , Váncsa S. , Papp M. , Janka T. , Gajdán L. , Liver Study Group of the Centre for Translational Medicine at
3
prospective parts, planned and carried out by the Hungarian
2
, Pár G.
University of Pecs. Liver transplantation centres from Central
1,2,5
Hegyi P. P. , Váncsa S. , Papp M. , Janka T. , Gajdán L. , Liver Study Group of the Centre for Translational Medicine at
Hegyi
3
4
1,2
3
1
and Eastern European countries will be asked to join the
1,2,5
, Pár G.
Hegyi P.
1. Institute for Translational Medicine, Medical School, University of Pecs. Liver transplantation centres from Central
2
1. Institute for Translational Medicine, Medical School,
Szentágothai Research Centre, University of Pécs, Pécs, project. In the retrospective cohort study, pre-defined forms
and Eastern European countries will be asked to join the
project. In the retrospective cohort study, pre-defined forms
Hungary; 2. Department of Gastroenterology, Medical will be used to collect data on medical history, physical
Szentágothai Research Centre, University of Pécs, Pécs,
School, University of Pécs, Pécs, Hungary; 3. Second status, signs and laboratory tests. Retrospectively
will be used to collect data on medical history, physical
Hungary; 2. Department of Gastroenterology, Medical
Department of Internal Medicine, University of Debrecen, sarcopenia, obesity, and SO will be assessed with a special
School, University of Pécs, Pécs, Hungary; 3. Second
status, signs and laboratory tests. Retrospectively
Debrecen, Hungary; 4. Szent György Teaching Hospital of software dedicated to estimating body composition based on
Department of Internal Medicine, University of Debrecen,
sarcopenia, obesity, and SO will be assessed with a special
Debrecen, Hungary; 4. Szent György Teaching Hospital of
County Fejér, Székesfehérvár, Hungary; 5. First Department CT scans of the patients who were on waiting list for LT. The
software dedicated to estimating body composition based on
County Fejér, Székesfehérvár, Hungary; 5. First Department
primary outcome will be post-LT survival. In the prospective
of Medicine, University of Szeged, Szeged, Hungary CT scans of the patients who were on waiting list for LT. The
cohort study, patients will be enrolled when signed up for the
of Medicine, University of Szeged, Szeged, Hungary primary outcome will be post-LT survival. In the prospective

Introduction: Non-alcoholic fatty liver disease (NAFLD) is cohort study, patients will be enrolled when signed up for the
waiting list of LT and data collection and measurements will
Introduction: Non-alcoholic fatty liver disease (NAFLD)
now recognized as the most prevalent chronic liver disease is waiting list of LT and data collection and measurements will
be carried out prospectively; data will be recorded in a patient
worldwide. About 15% of the NAFLD cases progress to non- registry. d out prospectively; data will be recorded in a patient
be carrie
now recognized as the most prevalent chronic liver disease
alcoholic steatohepatitis (NASH), which increases the risk of registry.
worldwide. About 15% of the NAFLD cases progress to non-

progressive fibrosis to cirrhosis and end-stage liver disease. Conclusions: Abnormal body composition has a substantial
alcoholic steatohepatitis (NASH), which increases the risk of
progressive fibrosis to cirrhosis and end-stage liver disease.
Purpose: The registry aims to clarify the prevalence, the risk negative impact on post-LT survival. Since a CT scan is
Conclusions: Abnormal body composition has a substantial
negative impact on post-LT survival. Since a CT scan
factors, and the outcomes of NAFLD/NASH. mandatory before LT, data are easily available to estimate is
Purpose: The registry aims to clarify the prevalence, the risk
factors, and the outcomes of NAFLD/NASH.
Methods: The registry for NAFLD/NASH diseases received mandatory before LT, data are easily available to estimate
body composition and the opportunity is given to arrange
countermeasures. and the opportunity is given to arrange
ethical and biobank permission in 2019 (TUKEB-59061- body composition
Methods: The registry for NAFLD/NASH diseases received
ethical and biobank permission in 2019 (TUKEB-59061-
5/2016/EKU). This multicenter, prospective, national registry countermeasures.
5/2016/EKU). This multicenter, prospective, national registry
will initially involve three centers in Hungary. Participation is 56. PRE-TRANSPLANT SARCOPENIC OBESITY

SARCOPENIC
LIVER
will initially involve three centers in Hungary. Participation is
PRE-TRANSPLANT
56.
voluntary and based on written consent. Any patient WORSENS THE SURVIVAL AFTER OBESITY
AFTER
THE
WORSENS
SURVIVAL
diagnosed with NAFLD/NASH disease will be included upon TRANSPLANTATION: A META-ANALYSIS AND A
LIVER
voluntary and based on written consent. Any patient
SYSTEMATIC REVIEW A META-ANALYSIS AND A
diagnosed with NAFLD/NASH disease will be included upon
gastroenterological presentation. Details from medical TRANSPLANTATION:
1,3
history, status, complaints, laboratory and imaging SYSTEMATIC REVIEW 1,2,3 , Szakács Z. , Hanák L. ,
3
Hegyi P. , Soós A. , Hegyi P.
3
3
gastroenterological presentation. Details from medical
3
history, status, complaints, laboratory and imaging
1 3
1,3
examination, and therapy will be prospectively collected on Hegyi P. , Soós A. , Hegyi P. 1,2,3 , Szakács Z. 3
3
3
1,3
Pétervári E. , Balaskó M. , Erőss B. , Pár G. , Hanák L. ,
when
enrollment. Blood sampling is pectively collected on Pétervári E. , Balaskó M. , Erőss B. , Pár G.
3
1,3
1. Division of Gastroenterology, First Department of
1
done
3
examination, and therapy will be pros
a
done
enrollment.
Medicine, Medical School, University of Pécs, Pécs,
is
sampling
when
gastroenterologist orders laboratory examination; no a 1. Division of Gastroenterology, First Department of
Blood
additional intervention will be needed. Follow-up is planned Hungary; 2. Clinical Medicine Doctoral School, University of
Medicine, Medical School, University of Pécs, Pécs,
gastroenterologist orders laboratory examination; no
for every participant at 6 and 12 months and then yearly to 5 Szeged, Szeged, Hungary; 3. Institute for Translational
additional intervention will be needed. Follow-up is planned
Hungary; 2. Clinical Medicine Doctoral School, University of
years, with the same structure as on enrollment. The registry Szeged, Szeged, Hungary; 3. Institute for Translational
for every participant at 6 and 12 months and then yearly to 5
years, with the same structure as on enrollment. The registry
53
53

Central European Journal of Gastroenterology and Hepatology 53
Volume 6, Supplementum 2 / November 2020