Page 42 - Magyar Gasztroenterológiai Társaság 2020. november 6–7. – ONLINE KONGRESSZUS

Előadáskivonatok / Abstracts

determine the role of presenting symptoms and risk factors swab (NPS) samples are the gold standard for diagnosis of
on the outcomes and severity of GIB. the disease. However, a more efficient method is
indispensable to test masses rapidly and cost-effectively.
18. CARBON BLACK TATTOO OF COLON CANCER Current literature indicates that saliva specimen collection
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Czepán M. , Lázár G. , Ábrahám S. , Paszt A. , Simonka Z. , could be a possible substitute to shorten the testing time for
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Andrási L. , Bor R. , Molnár T. , Lénárt Z. , Ollé G. , Szepes COVID-19 suspected cases.
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Z. , Róka R. , Csala B. , Tiszlavicz L. , Vasas B. , Kővári B. , Aims: To perform a systematic review and meta-analysis on
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Kaizer L. the consistency and reliability of viral RNA detection of
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1. 1st Department of Medicine, University of Szeged; 2. SARS-CoV-2 from saliva specimens.
Department of Surgery, University of Szeged; 3. Department Methods: The meta-analysis was performed according to
of Pathology, University of Szeged the Cochrane Handbook. Several major databases
(Cochrane Library, Embase, Pubmed, Scopus, Web of
Introduction: International societies of gastroenterology Science and clinical trial registries) were searched between
endorse endoscopists worldwide to use carbon black 1 January and 25 April 2020 for eligible papers. The number
colonoscopic marking or tattoo for lesions like malignancies of positive tests and the total number of tests performed were
even proven or suspected, polypectomy, EMR or ESD sites, extracted as raw data from each included record. The ratio
difficult-to-detect polyps or dysplastic areas. Relatively few of positive tests in the pooled data was evaluated using the
publications concerning the topic are mainly retrospective Freeman-Tukey transformation. Heterogeneity was
and some of them are poorly documented. Some authors measured using I and tests.
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state that carbon suspension is not drained to lymph nodes Results: The systematic literature search revealed 96
at all, some state the opposite, even that carbon tattoo helps records excluding duplicates. From these papers 26 were
staging by better visualisation and therefore dissection of included in qualitative and 5 records in quantitative synthesis.
lymph nodes. The latter feature could be of paramount The analysis showed that the sensitivity for saliva tests is
importance for clinical decision making since it could 91% (CI 80-99%), while sensitivity for NPS tests is 98% (CI
differentiate betweeen N0 and N1 stages and therefore could 89-100%) in previously confirmed COVID-19 patients. There
indicate the need for adjuvant oncotherapy. was a moderate heterogeneity among studies. Additionally,
Aims: We designed an open, prospective, randomised, 18 ongoing clinical trials were identified in the
controlled, phase IV, cohort study with primary outcome of ClinicalTrials.gov database. These records investigate the
improvement in staging defined as better pTNM stage via applicability of saliva-based testing for virus detection.
better visualisation of carbon marked metastatic or sentinel
lymph nodes or marked primary tumor or adjacent tissues on Conclusion: Saliva-based samples offer a highly promising
pathologic dissection of surgical specimen. The study is alternative to NPS test for detecting SARS-CoV-2. However,
approved by the Institutional Ethics Committe and revised by additional diagnostic accuracy studies are needed to further
ClinicalTrials PRS review as NCT03705754. investigate their specificity and sensitivity.
Methods: An opened, but permanent member based Acknowledgements: This work was supported by the
multidiciplinary team was formed to work for the above Hungarian Human Resources Development Operational
purpose. Program (EFOP-3.6.2-16-2017-00006).
Results: By the time the abstract was submitted, 20 patients
had undergone tattooing, had surgery, and histology 20. COELIAKIÁS BETEGEK ÉLETMINŐSÉGÉNEK
evaluation. Raw data processing shows for the primary VIZSGÁLATA
endpoint that carbon black tattoo marks lymph nodes Dakó E. , Papp V. , Dakó S. , Juhász M. , Pálfi E.
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irrelevant of metastatic or non-metastatic origin on a non- 1. Semmelweis Egyetem, Patológiai tudományok Doktori
statistical basis. However carbon mark distributed to the iskola, Egészségtudományok program; 2. Semmelweis
regional lymph nodes on a non-regular basis, it may help Egyetem, II. sz. Belgyógyászati Klinika; 3. Szent Margit
dissection for the pathologist. Conclusion: Conclusions can Kórház Budapest, IV. sz. Belgyógyászati Osztály; 4.
be made after full data processing. The authors will provide Semmelweis Egyetem, Egészségtudományi Kar,
full statistics as soon as possible. Alkalmazott Egészségtudományi Intézet, Dietetikai és
Táplálkozástudományi Tanszék
19. DIAGNOSING COVID-19 FROM SALIVA SAMPLES: A
SYSTEMATIC REVIEW AND META-ANALYSIS Introduction: A gluténmentes táplálkozással járó kihívások
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Czumbel L. , Kiss S. , Farkas N. , Mandel I. , Hegyi A. , hatással lehetnek a coeliakiások életminőségére.
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Nagy Á. , Lohinai Z. , Szakács Z. , Hegyi P. , Steward M. , Aims: Célunk a coeliakiás betegek életminőségének
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Varga G. követése.
1. Department of Oral Biology, Faculty of Dentistry, Methods: Követéses vizsgálatunk a Semmelweis Egyetem
Semmelweis University, Hungary; 2. Institute for II. számú Belgyógyászati Klinika és a Szent Margit Kórház
Translational Medicine, Medical School, University of Pécs, coeliakiás betegeinek bevonásával zajlik. A betegek
Hungary; 3. Doctoral School of Clinical Medicine, University többszöri kontrollon vesznek részt, amelyek során Dorn
of Szeged, Hungary; 4. Department of Dentistry, Oral and (2009) életminőség-mérő tesztje alapján összeállított
Maxillofacial Surgery, Medical School, University of Pécs, kérdéssort töltenek ki.
Hungary; 5. Department of Conservative Dentistry, Faculty of A 41 (31 nő, 10 férfi; 33,7 ± 11,7 év) fős mintában a 16
Dentistry, Semmelweis University, Hungary; 6. School of újonnan diagnosztizált beteg mellett, 25 régebb óta diétázó
Medical Sciences, University of Manchester, Oxford Road, szerepel. A régi betegek diagnózis óta eltelt ideje 7,3 ± 7,6
Manchester, the UK év.
Results: Az eredmények alapján kvartiliseket alkottunk;
Introduction: The SARS-CoV-2 causing COVID-19 is a életminőség „nagyon jó”, „jó”, „nem jó”, „rossz”.
dangerous and widely spread virus. Globally, as of 6 A régebb óta diétázók közül legtöbben (12 fő) „nagyon jó”,
September 2020 there have been 26 726 982 confirmed míg az újonnan diagnosztizált beteg fele (8 fő) 3 hónap diéta
cases, including 876 152 deaths. At present nasopharyngeal
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40 Central European Journal of Gastroenterology and Hepatology
Volume 6, Supplementum 2 / November 2020