Page 173 - A Magyar Szemorvostársaság 2023. évi kongresszusa - Tudományos program és előadáskivonatok

Age- and gender-dependent alterations of parameters to IOL calculation
Gergely Simó, Emília Orosz, László Szalay, Edit Tóth-Molnár
SZTE Szemészeti Klinika, Szeged

Introduction: The age-dependent alterations of biometric parameters may have an impact on
the long-term validity of the IOL calculation. The aim of our study was to investigate the age-
and sex-dependency of IOL-related parameters.

Methods: Our database contains data on 14,982 eyes of 7,491 patients aged 50 years or older
who underwent successful intraocular lens planning in both eyes using the IOLMaster500
biometer at the Department of Ophthalmology, University of Szeged between March 2013 and
June 2019. We examined the axial length (AL), anterior chamber depth (ACL), keratometric
(K), and horizontal corneal diameter (WTW) data, according to age and sex. Distinguishing
age-related changes, we formed groups based on age as 50-59, 60-69, 70-79, and 80-plus
years.

Results: AL showed an age-related reduction in both sexes (female / male, mean±sd:
23.62±1.96 / 24.06±2.00, 23.29±1.43 / 23.66±1.12, 23.07±1.07 / 23.57±0.94, and 22.97±1.00
/ 23.54±0.91 mm). Similarly, the corresponding values of ACD were also decreased (3.16±0.40
/ 3.26±0.36, 3.08±0.36 / 3.17±0.35, 2.99±0.35 / 3.09±0.37, and 2.88±0.33 / 2.98±0.34 mm). In
contrast to the increasing values of the horizontal components of K (43.70±1.62 / 43.15±1.52,
44.01±1.55 / 43.40±1.63, 44.29±1.53 / 43.74±1.49 and 44.57±1.44 / 43.89±1.42 D), the vertical
substances remained unchanged statistically (44.31±1.76 / 43.43±1.66, 44.37±1.69 /
43.50±1.68, 44.39±1.59 / 43.59±1.56, and 44.41±1.48 / 43.47±1.54 D). The WTW data
decreased by age (11.96±0.43 / 12.14±0.43, 11.90±0.44 / 12.06±0.45, 11.83±0.43 /
12.02±0.44 and 11.77±0.44 / 11.96±0.45 mm). The extent and direction of the averaged
corneal astigmatic refraction (dioptre (degree)) were changed by age and sex (female / male):
1.04 (70.76) / 0.74 (61.17), 0.81 (63.66) / 0.72 (51.05), 0.73 (50.68) / 0.69 (35.66), and 0.79
(36.38) / 0.88 (24.57).

Conclusion: We observed an age-related decrease of AL, ACD, and WTW, an increase of the
horizontal component of K, but no change in the vertical K values. As a result of these changes,
the corneal astigmatic vector, determined by standard keratometry, is shifted in the ATR
direction.